Role of Hypomagnesaemia in Acute Kidney Injury
Published: March 1, 2018 | DOI: https://doi.org/10.7860/JCDR/2018/28073.11329
Ventakarakesh Chintala, Venkataraya M Prabhu, Manaswitha Boyanagari, Ajay N Bhat
1. Junior Resident, Department of General Medicine, Kasturba Medical College, Mangaluru, Karnataka, India.
2. Professor and Dean, Department of General Medicine, Kasturba Medical College, Mangaluru, Karnataka, India.
3. Research Assistant, Department of General Medicine, Kasturba Medical College, Mangaluru, Karnataka, India.
4. Assistant Professor, Department of General Medicine, Kasturba Medical College, Mangaluru, Karnataka, India.
Correspondence
Dr. Ajay N Bhat,
Assistant Professor, Department of General Medicine, Kasturba Medical College, Mangaluru-575001, Karnataka, India.
E-mail: ajaybhatmj53363@yahoo.co.in
Introduction: Acute Kidney Injury (AKI) is a common problem with various causes and consequences like electrolyte disturbances in the form of hypocalcaemia, hypokalemia, hyperkalemia depending on the phase. Serum magnesium concentration of <1.5 meq/L is defined as hypomagnesaemia and is one of the common electrolyte abnormality. Serum magnesium levels are not routinely done in AKI cases.
Aim: The aim of our study was to assess the role of hypomagnesaemia as a risk factor for non recovery of AKI.
Materials and Methods: A cross-sectional study was conducted between July 2014 and August 2015 with a sample of 100 patients. The decrease in magnesium <1.5 meq/L was defined as hypomagnesaemia. AKI was defined as per KDIGO criteria. Day 1, day 3 and day 6 magnesium levels were measured.
Results: Prevalence of hypomagnesaemia was 69%, 43% and 27% on day 1, day 3 and day 6 respectively. It was observed that hypomagnesaemia on day 1 was significantly associated with recovery of AKI (p=0.004).
Conclusion: Prevalence of hypomagnesaemia was significantly higher in AKI patients and hypomagnesaemia on day 1 was associated with recovery. However, magnesium levels on day 3 and day 6 had no significant correlation with the renal function in AKI.
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